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ESI-09 inhibits pancreatic cancer cells AsPC-1 and PANC-1 migration
with a slow continuous release of the hormone to follow for approximately 21 days
acts by repair of transient radiation-induced oxidative species on DNA
Pakhomov N
placebo-controlled trial
Bivalirudin trifluoroacetate - CAS# 128270-60-0 carpine ESI-09 inhibits pancreatic cancer cellsBivalirudin, also known as BG 8967, is a specific and reversible direct thrombin inhibitor (DTI). Chemically, it is a synthetic congener of the naturally occurring drug hirudin (found in the saliva of the medicinal leech Hirudo medicinalis). Bivalirudin overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It